will concentrate on fundamental and applied research on
flow-based systems and non-flow-based (discrete or batch-wise or
semi-flow or conveyer belt type) systems with the main objective
to satisfy the needs of an end-user with an intelligent
interactive reliable low cost efficient process system.
Validation of the results (accuracy and precision) of the final
optimized methodologies involved in the end-product will depend
solely on the discussions with the end-users and their
requirements. This may vary from very high quality analysis (and
purity) with a high precision and accuracy such as in final
products to screening results (needing only a yes or no or in
certain process streams where there is a difference allowed
between the upper and lower ranges). Depending on the needs of
the end-user, the program will focus on:-
● Truly representative sampling.
Speed and truly, fully representative sampling is a key issue in
any entire operating system and differs from process to
process. Process streams in different parts of a petroleum
refinery, in chemical processes, waste waters, beverages, food,
pharmaceutical manufacturing, blood streams etc. differ and
should be studied.
● Sample manipulation.
Once a sample has been extracted from the operating system, it
must be transferred to the sensing part of the analyzer with the
assurance that it is still truly representative. The following
aspects will be studied, developed and optimized to be reliable
for long periods of time.
A preconditioning system if necessary, situated close to the
sampling point, may be used to treat the sample in such a way to
eliminate problems, for example by solid particles, droplets or
condensates, which may lead to blockage or fouling of the
sample-transport line and to regulate the pressure and
temperature of the sample provided to the system.
The sample-transport line, if necessary, must transport the
sample from the preconditioning point to the analyzer in an
acceptable time and without the composition of the sample being
affected appreciably. Speed and representativeness are the keys
The sample-conditioning modules, if necessary, are designed to
ensure that the sample is acceptable to the analyzer, that it is
still truly representative and that the analyte (or analytes) is
correctly adjusted or processed and/or separated and in the best
position to be detected by the sensing part of the analyzer.
● Multi-point multi-species real-time measurements or
multi-analyte real-time platforms.
These fundamental and applied studies will focus on the
construction, behaviour and development or adaption of
sensors/atomic force/imaging/spectroscopic devices suitable for
at-line or on-line or in-line, non-invasive/invasive,
non-destructive/destructive real-time measurements either
single-point single species, but ideally multi-point
latest PATLAB technology is the development of multi-analyte
real-time platforms where nanotechnology can play a very
● Flow-based synthesis.
These studies will be devoted to micro-multistep
flow-based devices with the concept of zone fluidics with the
main objective the creation of a high value added high quality
pure product (or products) using multi-point multi-species
real-time measurements from raw material via intermediates to
● Intelligence interactive management and
These fundamental and applied studies will focus
on all aspects of research and development of process systems
for intelligence interactive monitoring and control and small
scale synthesis with advantages of the technology and
applications in informatics, mathematics, statistics and
chemometrics using computer and information sciences with data
acquisition, processing and transfer and automatic feedback
process control strategies with intelligence interactive
management and control.